Senna for Constipation

A 2021 study found that senna was similarly effective to magnesium oxide and superior to placebo at treating chronic constipation daily over 28 days. No serious adverse events were seen. Senna may cause stomach upset or other side effects.

Morishita D, Tomita T, Mori S, Kimura T, Oshima T, Fukui H, Miwa H. Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial. Am J Gastroenterol. 2021 Jan 1;116(1):152-161. doi: 10.14309/ajg.0000000000000942. PMID: 32969946.