Hyperbaric Oxygen Therapy for PTSD

A 2024 study found that hyperbaric oxygen therapy (HBOT) was significantly more effective than sham protocol at treating combat-associated PTSD over 14 weeks. Symptoms of depression improved significantly as well. Studies have shown this improvement can last for years after treatment. Brain imaging has also shown improved connections with HBOT treatment. It’s important that HBOT is conducted under appropriate medical supervision.

Doenyas-Barak K, Kutz I, Lang E, Assouline A, Hadanny A, Aberg KC, Levi G, Beberashvili I, Mayo A, Efrati S. Hyperbaric Oxygen Therapy for Veterans With Combat-Associated Posttraumatic Stress Disorder: A Randomized, Sham-Controlled Clinical Trial. J Clin Psychiatry. 2024 Nov 10;85(4):24m15464. doi: 10.4088/JCP.24m15464. PMID: 39566051.

Doenyas-Barak K, Catalogna M, Kutz I, Levi G, Hadanny A, Tal S, Daphna-Tekoha S, Sasson E, Shechter Y, Efrati S. Hyperbaric oxygen therapy improves symptoms, brain's microstructure and functionality in veterans with treatment resistant post-traumatic stress disorder: A prospective, randomized, controlled trial. PLoS One. 2022 Feb 22;17(2):e0264161. doi: 10.1371/journal.pone.0264161. PMID: 35192645; PMCID: PMC8863239.