Medical Marijuana for Alzheimer’s Disease

A 2025 study found that a low dose oral cannabis extract (0.350 mg of THC and 0.245 mg of CBD) was significantly more effective than placebo at improving cognitive assessment scores over 26 weeks in people ages 60-80 years old with Alzheimer’s disease. Marijuana can cause lightheadedness, nausea or other side effects. It can also significantly interact with certain medications like Warfarin. Marijuana is not recommended for people at increased risk for psychosis. Marijuana is not safe during pregnancy. Marijuana is federally illegal.

Cury RM, da Silva T, Cezar-Dos-Santos F, Fakih YRC, Narvaez KAR, Gouvea MC, Espínola C, Ferreira CF, de Castro WAC, Pamplona FA, Silva EGD, Bicca MA, Nascimento FP. A randomized clinical trial of low-dose cannabis extract in Alzheimer's disease. J Alzheimers Dis. 2025 Dec;108(4):1602-1613. doi: 10.1177/13872877251389608. Epub 2025 Oct 29. PMID: 41160460.