Calendula Cream for Contact Dermatitis

A 2025 study found that a 1% cream of calendula was significantly more effective than placebo at improving hydration and skin barrier integrity over 8 days in people with contact dermatitis. Studies have also shown significantly faster wound healing and reduced wound pain with topical calendula. Some people may be allergic to calendula.

Crnčević MŠ, Durdov T, Rušić D, Ramić L, Ćosić A, Bukić J, Jokić S, Aladić K. Double-blind randomised controlled trial of an emollient cream with and without 1 % supercritical CO2 extract of Calendula officinalis in contact dermatitis. Acta Pharm. 2026 Jan 13;75(4):699-708. doi: 10.2478/acph-2025-0035. PMID: 41527980.

Giostri GS, Novak EM, Buzzi M, Guarita-Souza LC. Treatment of acute wounds in hand with Calendula officinalis L.: A randomized trial. Tissue Barriers. 2022 Jul 3;10(3):1994822. doi: 10.1080/21688370.2021.1994822. Epub 2021 Oct 21. Erratum in: Tissue Barriers. 2022 Jul 3;10(3):2056359. doi: 10.1080/21688370.2022.2056359. PMID: 34674610; PMCID: PMC9359387.

De Angelis C, Di Stadio A, Vitale S, Saccone G, Angelis MC, Zizolfi B, Di Spiezio Sardo A. Use of calendula ointment after episiotomy: a randomized clinical trial. J Matern Fetal Neonatal Med. 2022 May;35(10):1860-1864. doi: 10.1080/14767058.2020.1770219. Epub 2020 May 27. PMID: 32460565.